Overview
High-Throughput Cell Culturing and Fermentation Testing
Using a 24-chamber microplate bioreactor vessel with the footprint of a standard microplate, the AutoReact™ system automatically loads samples and feeds cells growing under 24 independent reaction conditions simultaneously. The fully-automated run frees the user from any need to manually sample or monitor any of its 24 reactions, even for runs lasting days. Users can input an unlimited number of test conditions to trigger automated feeding and/or sampling of the chambers’ contents, while maintaining the sampled amounts in a chilled environment for the entire length of the run. The AutoReact™ is ideal for clone screening and selection, protein production for research applications, and media development and improvement for both research and manufacturing applications.
Features
- Users input unlimited number of test conditions to trigger automated feeding and/or sampling
- Maintains samples in chilled conditions until the user elects to remove them for analysis
- Automatically loads/unloads sampling microplates without manual intervention
- Eliminates the need for operator monitoring and late-night attendance for sampling and feeding
- The system is programmed to take readings of critical, user-selectable process conditions to determine the need for individual reactor tube sampling and/or feeding
- The system software provides an easy-to-use GUI enabling the input of condition algorithms which will be evaluated against actual measured process parameters to determine the need for and required volume of samples and/or feed media in each tube at any time
- Includes Hudson Robitcs’ SoftLinx software, which provides an easy-to-use interface to coordinate the AutoReact’s operation with other automated instruments
- Sample plate capacity of 30 standard-height microplates
- Up to 7 feeding media reservoirs
- Users can add new sample plates, remove filled plates, and change sampling and feeding conditions anytime during a run